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Biostimulators
In aesthetic medicine, biostimulators are primarily used as injectables to address signs of aging by encouraging the body to produce its own supportive tissues, such as collagen and elastin. This results in gradual, natural-looking, and long-lasting improvements to skin quality and volume. Biostimulators work through different biological pathways, often categorized as either replacement (triggering a mild inflammatory response to replace volume) or regeneration (restoring native tissue structure).
Sculptra, an FDA-approved injectable biostimulator composed of poly-L-lactic acid (PLLA), restores facial volume by stimulating your body’s natural collagen production. Unlike traditional hyaluronic acid (HA) fillers (such as Juvéderm), which offer immediate physical volume, Sculptra gradually rebuilds the skin’s internal structure. Improvements typically appear over 4 to 6 months.
Radiesse, an FDA-approved injectable dermal filler, is primarily used to smooth moderate-to-severe facial wrinkles and folds, such as nasolabial folds, and to restore volume in the back of the hands. Unlike traditional hyaluronic acid (HA) fillers, Radiesse functions as a biostimulator, offering both immediate volume and long-term collagen production with results lasting between 12 and 18 months.
